Ok. Lets see what we learned, by the numbers, so to speak.
Two - She has a daughter somewhere. The daughter is part Two and part Irena Shaw. She was left in the care of someone named Cryden.
Three - Sarah contracted her illness and died because of him. In short, he killed her slowly and painfully. Just not on purpose. But knowing that was too much for him to bear. So he intentionally let his clone get killed, thus he remembers nothing of what Ryo told him.
Five - As it turns out, she has met her sister before. But she was running away at the time (to the Raza). We still don't know what the picture Ryo showed her was, or why she was so upset over it.
Six - As it turns out, it was GA the whole time he couldn't trust. The same person responsible for 6 killing 10,000 innocent people was the same one that sold him out to Portia.
And lets not forget the Android rebellion. It's already started, and they have already started killing humans.
Lastly is the fate of Ryo. Does two kill him? Obviously no. Can't wait till this Friday!!!!!